Rejuran Injections (PDRN)
Reviews
Next-Level Skin Repair, Powered by Salmon DNA
What if your skin didn’t just look younger—but acted younger, too? Powered by PDRN, a regenerative molecule derived from purified salmon DNA (yes, really!), Rejuran delivers deep healing benefits beneath the surface. Loved by skincare pros, K-beauty fans, and beauty insiders, PDRN is known as the ultimate “skin healer injection.”
At Luxe Medical Aesthetics in Katy, TX, we offer Rejuran to boost elasticity, calm inflammation, and restore your natural glow. Whether you’re looking to reduce fine lines, improve texture, or balance out your tone, this cutting-edge injectable might be your secret weapon.

What Is Rejuran?
Rejuran is a breakthrough skin rejuvenation treatment featuring PDRN, a DNA fragment sourced from salmon that’s rich in polynucleotides (PN)—the essential building blocks of healthy skin. Rather than masking imperfections, it helps your skin repair itself, enhancing elasticity, smoothing texture, and restoring that youthful, radiant glow. The result? Skin that’s stronger, smoother, and more resilient over time.
While not FDA-approved in the U.S. (yet!), PDRN is widely used throughout Asia—especially in South Korea, a global leader in skincare innovation. Backed by clinical studies, it’s praised for its safety, efficacy, and ability to deliver visible results with little to no downtime.
What Can Rejuran Treat?
Rejuran is versatile and effective for a variety of skin concerns, including:
- Fine lines and early wrinkles
- Enlarged pores
- Uneven skin texture
- Acne scars and post-inflammatory pigmentation
- Dull, dehydrated skin
- Thin or crepey skin on the neck and under the eyes
- Skin redness and sensitivity
- Skin barrier damage from over-exfoliation or procedures
Horizontal lines that develop across the forehead due to repeated raising of the brows, making the face appear aged or stressed.
Vertical lines that form between the eyebrows from repeated frowning or squinting, giving a perpetually angry or tense look.
Fine lines radiating from the outer corners of the eyes that deepen with smiling or squinting, often one of the first signs of aging.
Small diagonal wrinkles that appear on the bridge of the nose when scrunching the face, particularly when laughing or smiling.
When excessive gum tissue is exposed while smiling, Dysport can relax the upper lip to create a more balanced, aesthetically pleasing smile.
Enhances the upper lip by relaxing the muscles around the mouth, causing the lip to slightly roll upward for a fuller, natural-looking effect.
Also known as “orange peel” chin, caused by overactive mentalis muscles leading to an uneven, textured appearance that Dysport helps smooth out.
Vertical lines or cords on the neck that become more prominent with age due to muscle contractions, which Dysport softens for a more youthful neckline.
How Rejuran Works
Rejuran works at a cellular level to support deep skin healing and regeneration. Its star ingredient, PDRN, is known for its anti-inflammatory and wound-healing properties, perfect for calming irritation and reversing damage from aging, sun exposure, or environmental stress.
It works by interacting with adenosine A2A receptors to help reduce inflammation. It also supplies essential DNA fragments—nucleosides and nucleotides—through what’s called the “salvage pathway,” a natural process your body uses to rebuild and repair tissue. Over time, this deep healing leads to visible improvements in tone, texture, and resilience, giving you skin that’s not just glowing—but thriving.
Rejuran Benefits
Deep Skin Repair
Unlike surface-level treatments, Rejuran heals from the inside out—restoring structure and vitality where damage actually lives: deep in the dermis.
Improved Skin Barrier Function
If your skin freaks out over everything? Rejuran helps rebuild the barrier, reducing sensitivity and boosting your skin’s ability to protect itself.
Boosted Collagen & Elasticity
No, this isn’t just about plumping. It’s about resilience. Rejuran encourages firmer, more elastic skin—so you bounce back quicker from stress, aging, and environmental damage.
Long-Term Regeneration
Rejuran doesn’t just fade problems temporarily—it retrains your skin to act younger, healthier, and stronger over time.
Minimal Downtime
No lasers, no peeling, no weeks of hiding. Most patients experience mild redness or swelling for 24-48 hours—then it’s back to life as usual.
Natural-Looking Results
Rejuran enhances your skin—no puffiness, no overfilled look. Just smoother, brighter, and naturally healthier skin you can feel good in.
Rejuran Treatment Process: What To Expect
Before Your Treatment
Every treatment at Luxe Medical Aesthetics starts with a personalized consultation. We’ll assess your skin health, discuss your goals, and design a tailored treatment plan. We may recommend prepping your skin with hydration or barrier-repair products to enhance results.
During Your Treatment
On treatment day, a topical numbing cream is applied for comfort. Using ultra-fine needles or a mesotherapy device, Rejuran is precisely injected into the dermis in microdroplets. The procedure typically takes 30–45 minutes and is well tolerated by most clients.
After Your Treatment
Expect some mild redness, swelling, or pinpoint marks immediately after but nothing that’ll stop your day. We’ll provide you with post-care tips to optimize healing (spoiler: lots of hydration and SPF). Most clients resume normal activities within 24 hours.
Results Timeline
You’ll begin to notice smoother texture and better hydration within 1–2 weeks, with more significant improvements appearing over 4–6 weeks. For best results, we recommend a series of 3–4 treatments spaced about a month apart, followed by maintenance every 4–6 months.

Am I a Good Candidate for Rejuran?
Rejuran is ideal for anyone looking to repair, rejuvenate, and restore their skin—especially if you’re noticing signs of aging, damage, or sensitivity.
You may be a great candidate if you:
Have fine lines, acne scars, or dull skin
Struggle with sensitivity or poor barrier function
Want natural results without heavy fillers or lasers
Are looking for a long-term skin health solution
Contraindications include pregnancy, active infections, or autoimmune disorders. As always, a consultation is the best way to determine if Rejuran is right for you.
Rejuran FAQ
Is Rejuran the same as dermal fillers?
Nope. Rejuran doesn’t add volume like fillers do. It focuses on healing and regeneration—making your skin behave younger, not just look plumper.
Do Rejuran injections hurt?
Most clients describe the procedure as mildly uncomfortable, not painful. Numbing cream is applied beforehand, and we use fine needles to keep things as gentle as possible.
How many Rejuran treatments will I need?
We typically recommend a series of 3–4 sessions spaced about 4 weeks apart. After that, maintenance treatments every few months will help keep your skin thriving.
Can I combine Rejuran with other treatments?
Absolutely. Rejuran pairs beautifully with microneedling, light peels, and laser treatments to amplify results. We’ll customize a plan based on your goals.
Are there any side effects after Rejuran injections?
The most common side effects are mild redness, swelling, or small bumps at injection sites, which typically resolve within a day or two. Serious reactions are rare.
Is Rejuran safe?
Yes—Rejuran has a strong safety profile and has been used extensively in clinical settings across Asia. The polynucleotides are purified and biocompatible, meaning they integrate safely into your skin without adverse reactions.
Fuel Your Skin’s Comeback with Salmon DNA
If you’re tired of treatments that promise a glow but don’t deliver real change, Rejuran might be your skin’s new best friend. At Luxe Medical Aesthetics, we believe in treatments that work smarter, not harder—reviving your skin from within.